Possibilities is to reduce the size of the unknown portion of the With increasing mass the number of elemental combinations In this case for the purpose of elemental composition determination exact mass measurements are performed on moleculesīelow 500 amu with a required mass accuracyĪt or better than 5 mmu. Higher mass accuracy is always helpful. Measurement for a molecule which is essentially unknown is very difficult. Determining elemental composition from an exact mass Little bit of knowledge about the molecule can help you restrict the number of returns obtained from an elementalĬalculator. Small molecule, what are the functional groups?" Use UV, IR, NMR, chemical modification, enzymeĭigest, or N-terminal protein sequencing to try and answer a few of Protein?", "Is it a small molecule?", "If it is a It helps to know as much as possible about Mass Measurement and Elemental Composition DeterminationĬomposition for an unknown compound from an exact mass measurement
0 Comments
Leave a Reply. |